South Africa vaccinations: which ones do you need?

Are you planning a trip to South Africa? Then it is important to make proper preparations. We recommend vaccinations for South Africa. The right vaccinations can protect you against tropical diseases that do not occur in the Netherlands.

South Africa is a beautiful country in the southern tip of Africa and is renowned for the wide variety of wildlife, breath taking nature and its friendly people. The largest part of the country has a so-called semi-arid climate. Along the coast – for example in lively Cape Town – the climate is subtropical. Even though the temperatures are not extremely high in summer – and not extremely low in winter – some tropical diseases occur. In short, whether you are travelling to South Africa for a safari, a round trip or to play golf, make sure you get the appropriate vaccinations before departure. Our nurses will gladly inform you about the required immunisations and vaccines for South Africa. Moreover it is important to know that malaria and dengue mosquitoes are present in South Africa. Our nurses are happy to advise you about these and other health risks. Click here to make an appointment (in Dutch) with one of our nurses.

South Africa vaccinations: the most common risks

Our experts have put together a list of vaccinations that are recommended for South Africa. Below you will find an overview of the most common risks and diseases, including the immunisations that can protect you against these. You can see at a glance which specific vaccinations you require and what additional precautions you can take.


In this country dengue fever is prevalent. A good protection against mosquito bites in the daytime is necessary.


Vaccination against DTP is recommended for all travelers to this country.

Hepatitis A

Vaccination against hepatitis A is recommended for all travelers to this country.

Hepatitis B

Vaccination against hepatitis B depends on your personal situation. Please contact KLM Health Services for a personal advice.


In this country there is a risk of getting malaria. Protection against mosquito bites is necessary during day- and nighttime. Sometimes malaria tablets are recommended, please contact KLM Health Services.


Mumps, Measles and Rubella (MMR) vaccination (BMR vaccination in Dutch) is recommended for travelers to this country who are not protected against measles yet. This includes children from 6 months and up who have not yet received their childhood MMR immunization.


Vaccination depends on your personal situation. In this country mammals could be infected with Rabies. Avoid contact with mammals. Please contact KLM Health Services for good and personal advice.


In this country Schistosomiasis is prevalent. Please contact KLM Health Services for personal advice.


Vaccination against tuberculosis depends on your personal situation. Please contact KLM Health Services for personal advice.

Yellow Fever - possibly compulsory

In this country Yellow Fever is not prevalent. However, when you’re traveling FROM a Yellow fever area vaccination can be COMPULSORY. Please contact KLM Health Services to discuss or vaccination applies to you.

A healthy trip to South Africa? Prepare for your trip with our tips

Make your trip to South Africa as pleasant as possible and avoid unexpected surprises. Below you will find helpful tips and tricks to prepare yourself for your journey.

Our KLM Health Services’ Doctor Connect service allows your to contact a KLM Health Services expert 24/7, either by telephone, text message or WhatsApp. Not only in case of emergency but also if you have doubts. Subscribe to Doctor Connect.

Seemingly innocent things such as food, water and bright sunlight can pose a risk to your health during your travels. Want to know what measures you can take to reduce these health risks? Please read our travel tips.

The Dutch Ministry of Foreign Affairs travel advice (in Dutch) helps you prepare for safety risks during your stay abroad. The travel advice, for example, tells you which regions are safe and to which regions you should not travel. Sometimes there are security risks. If this is the case, please be alert or, preferably only travel to the country concerned if genuinely necessary. The Dutch Ministry of Foreign Affairs has set up a central telephone number for travellers, which can be reached 24/7. Please call: +31 247 247 247.

Schedule a vaccination for South Africa? Make an appointment!

Please make an appointment online for your South Africa vaccinations. An overview of our branches can be found here. Do you have any other questions about immunisations for South Africa? Please feel free to contact us and send an email to You can also visit our frequently asked questions page.

Vaccination required for the above risks?

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